Endocrinology · Physical Diagnosis PDX

Abdominal Striae

3 patients · 5 clips

Atrophic linear bands of skin, with a tendency to occuring the abdomen. Unlike the striae in simple obesity, the striae of Cushing’s syndrome are thicker (> 1cm) and violaceous (due to dermal thinning). Endocrinology Pat

Abdominal Striae (Obesity)

1 patients · 1 clips

The abdominal striae of Cushing’s syndrome are wide and purple in color, in contrast to the pale or pinkish striae of obesity. Endocrinology Patient 1: This patient has abdominal striae related to obesity. Note that in c

Brisk Reflexes

1 patients · 2 clips

Seen in thyrotoxicosis as well as upper motor neuron lesions. Patient 1: This is an older woman with thyrotoxicosis from Graves’ disease. This patient also has Graves’ dermopathy.

Coarse Facies

2 patients · 4 clips

Patients have coarse facial features as a result of soft tissue and cartilage overgrowth. Endocrinology Patient 1: This is a young woman who was admitted to the hospital for surgical removal of a pituitary tumor after be

Macroglossia

1 patients · 2 clips

Patient 1: This is a middle-aged woman with hypothyroidism.

Multiple Endocrine Neoplasia Type 2b

1 patients · 1 clips

Autosomal dominant syndrome characterized by medullary thyroid carcinoma, pheochromocytoma,and mucosal neuromas. Patients may also have a marfanoid body habitus. Hereditary Conditions Tutorial Patient 1: This patient has

Delayed Relaxation Phase of Reflexes

4 patients · 6 clips

Delayed relaxation phase of reflexes is a sign of hypothyroidism. Often better seen in the Achilles, particularly with the patient kneeling on a chair. Endocrinology Patient 1: This patient has a delayed phase of the pat

Frontal Bossing

1 patients · 1 clips

Enlarged supraorbital ridges seen in acromegaly. Endocrinology Patient 1: This is a young woman who was admitted to the hospital for surgical removal of a pituitary tumor after being diagnosed with acromegaly. She experi

Saber Shins

1 patients · 2 clips

Sharp anterior bowing of the tibia. Endocrinology Patient 1: This patient has saber shins.

Bruising

2 patients · 2 clips

The thin skin associated with Cushing’s syndrome makes these patients susceptible to easy bruising. Endocrinology Patient 1: This is a previously healthy young man who presented with rapid weight gain and was ultimately

Goiter

1 patients · 4 clips

Goiters are enlarged thyroid glands, which are found in 10% of women and 2% of men. The normal thyroid weighs between 15 and 25 grams, and each lobe is 4-6 cm in length and 1.3-1.8 cm thick. Worldwide, the cause is inade

Buffalo Hump

1 patients · 2 clips

Fatty deposition in the dorsocervical fat pad. Endocrinology Patient 1: This is a previously healthy young man who presented with rapid weight gain, and was ultimately diagnosed with Cushing’s syndrome from an ectopic so

Graves’ Dermopathy

1 patients · 3 clips

Patient 1: This patient has Graves’ dermopathy findings in his lower limbs.

Macrognathia

1 patients · 2 clips

The mandible grows more rapidly than the maxilla causing the prognathism and the finding of widely spaced teeth in the mandible more often than the maxilla. Endocrinology Patient 1: This is a middle-aged woman with acrom

Hyperpigmentation

2 patients · 3 clips

Hyperpigmentation can be a sign of ACTH-independent (primary) adrenal insufficiency. High levels of ACTH found in these patients stimulate the melanocortin-1 receptor in the skin, resulting in hyperpigmentation. It tends

Queen Anne’s sign

1 patients · 1 clips

Thinning of the eyebrows, particularly the lateral third (known as the Sign of Hertoghe or Queen Anne’s sign). Endocrinology Patient 1: This is a young woman who was admitted to the hospital with delirium following month

Soft tissue enlargement

1 patients · 3 clips

Enlarged hands and feet with thickened heel pads. Patients are said to have a “doughy” handshake. Often this is when the diagnosis is first entertained by the astute physician as the sensation is so distinct. Endocrinolo

Moon Facies

1 patients · 1 clips

Moon Facies is a finding seen in Cushing’s syndrome. It causes fatty deposition in the bitemporal regions. Often when sitting at eye level with your patient the deposition will hide their ears from your view. Endocrinolo

Slow Speech

1 patients · 1 clips

Patient 1: This is a middle aged woman with a history of hypothyroidism who was admitted for confusion and found to have multiple signs of severe hypothyroidism and a TSH in the 200s. Findings included slow, slurred spee

Soft tissue enlargement-Large feet

1 patients · 2 clips

Enlarged hands and feet with thickened heel pads. Patients are said to have a “doughy” handshake. Often this is when the diagnosis is first entertained by the astute physician as the sensation is so distinct. Image of la

Soft tissue enlargement-Large hands

3 patients · 3 clips

Enlarged hands and feet with thickened heel pads. Patients are said to have a “doughy” handshake. Often this is when the diagnosis is first entertained by the astute physician as the sensation is so distinct. Image of la

Thin Skin

4 patients · 6 clips

Dermal atrophy (cigarette paper thin) due to steroid inhibition of collagen synthesis. Thin skin is established when a skin fold over the proximal phalanx of the middle finger of the nondominant hand is <2 mm thick. This

Eruptive Xanthoma

4 patients · 4 clips

Red/yellow papules that may be found in patients with extremely elevated triglycerides. Endocrinology Patient 1: This patient has Patient 1: This patient has Patient 2: This patient has Patient 3: This patient has

Xanthlasma

1 patients · 3 clips

Patient 1:

Prayer Sign

2 patients · 4 clips

Can be a physical finding of diabetes, related to a condition called diabetic cheiroarthropathy. This results in stiffness of the joints preventing the fingers from opposing each other in a prayer position. This finding

Central Retinal Artery Occlusion

1 patients · 1 clips

Central retinal artery occlusion is the blockage of blood to the retina of one eye that usually causes sudden loss of eyesight in that eye. Patient 1: This patient has Central Retinal Artery Occlusion. In this image, che